Bruce verchere lab. Francis Lynn & Dr.
Bruce verchere lab. Peter Zandstra (UBC) There are many new treatments on the horizon for T1D, including those that block autoimmunity or replace insulin-producing cells. Feb 26, 2008 · The lawyer acting for Bruce Verchere in these grinding, emotional negotiations was Claude-Armand Sheppard, the same lawyer who, acting for the federal government, questioned Brian Mulroney three years later when Mulroney sued the government and the RCMP for libel. Bruce Verchere from University of British Columbia. Bruce Verchere at BC Children’s Hospital. Philipp Lange Dr. Proinsulin processing includes removal of several C-terminal basic amino acids and Mar 1, 2013 · Bruce Verchere Four faculty members were honoured by the Canadian Diabetes Association (CDA) with Queen Elizabeth II Diamond Jubilee medals: Bruce Verchere, a Professor in the Department of Surgery and the Department of Pathology and Laboratory Medicine, is the Head of the Diabetes Research Program Dr. ca - Homepage Diabetes Bruce Verchere, University of British Columbia Pathology and Laboratory Medicine Professor Vancouver, British Columbia verchere@interchange. Christopher Maxwell Dr. Pallo, Galina Soukhatcheva, Dai Lei, View ORCID ProfileMelena D. ca 22 21 *Co-Senior Authors 25 24 23 Word count: 4,770 Nov 1, 2003 · Address correspondence and reprint requests to Dr. The focus of the Chantler laboratory is Congratulations Bruce Verchere !! You have always been an inspiration for all of us! The best! Jay Rajadas Founding Faculty Director of ADDReB, Cardiovascular Institute /Pulmonary at Stanford Congratulations to BCCHR investigators Dr. In humans, few beta-cell epitopes have been reported, thereby limiting the study of beta-cell-specific CTLs in type 1 diabetes. Bruce Verchere as the Director of the Centre for Molecular Medicine and Therapeutics (CMMT). I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune At the Bruce Verchere lab, Heather Denroche, provided expertise in preclinical human islet transplantation models to help test a novel therapeutic antibody for type 2 diabetes in this Nature Communications paper. 2490 Fax: n/a Email: verchere Nov 14, 2022 · Raelyn Gallant, Researcher, Dr. Facebook gives people the power to share and makes the world more open and connected. Centre for Molecular Medicine and Therapeutics, University of British Columbia, 15 Vancouver BC, Canada, V6H 0B3 16 7. Bruce Verchere PositionDirector Location Vancouver, British Columbia Contact infob*********** [email protected] Safia PositionPhD Candidate, Medical Genetics Location Ontario, Canada Contact infos*** [email protected] Alice Huang PositionTaubert Lab Volunteer Location Contact infoa******** [email protected] Jeffy Rajan PositionVolunteer Location: BC Children’s Hospital Research Institute Supervisor: Bruce Verchere Glucagon-like peptide 1 (GLP-1) is a hormone that has received significant attention as a therapy for diabetes because of its ability to stimulate insulin biosynthesis and release and to promote growth and survival of insulin-producing β cells. She was a computer software entrepreneur whose innovative systems revolutionized office management throughout North America. He has served as a close JDRF International advisor for many years. S. The focus of the Chantler laboratory is Sep 15, 2023 · Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type 1 diabetes. ca/leadership-upd… Dr. #Correspondence and reprint requests may be addressed to: Dr. Bruce Verchere 6 days ago · Auburn basketball has announced that coach Bruce Pearl is retiring ahead of the Tigers' 2025-26 season. Bellin, View ORCID ProfileC. %A Murphy,Julia M. Carl De Boer Oct 16, 2020 · Gut Microbiota as a Trigger for Metabolic Inflammation in Obesity and Type 2 Diabetes Torsten P. " Dec 8, 2021 · “The JDRF Centre of Excellence at UBC will transform Type 1 diabetes research in Canada, sparking new collaborations, removing barriers and accelerating progress toward a cure,” says Dr. “I loved the analysis, the science of teasing apart what answers the data are telling you,” she said Dec 8, 2021 · Dr. G227 – 2211 Wesbrook Mall Vancouver, BC Canada V6T 2B5 Type 1 diabetes results from the autoimmune destruction of insulin-producing pancreatic beta-cells by cytotoxic T-lymphocytes (CTLs). The progressive loss of β-cell function in islet At Integrated Nanotherapeutics Inc. Levings, 2 Paul C. ca or Bruce Verchere, 20 19 bverchere@bcchr. Brodie Sakakibara Canadian Institutes of Health Research Project Grant Read More Dr. He is also head of the Diabetes Research Program at the Child & Family Research Institute, and holds the Irving K Barber Chair in Diabetes Research. Bruce Verchere 1,2 1 Departments of Pathology and Laboratory Medicine, Child and Family Research Institute, 2 Department of Surgery, and 3 Department of Cellular and Physiological Sciences, University of British Columbia Dr. ca The Research Both the Chantler and Verchere laboratories are part of the Diabetes Research Program at the Child and Family Research Institute in Vancouver, British Columbia. Courtade, Evan Y. Bruce Verchere Canadian Institutes of Health Research Fall 2024 Project Grant Read More Dr. Barber Chair in Diabetes Research at the University of British Columbia will present: 12 likes, 0 comments - bcchresearch on June 19, 2025: "Congratulations to BCCHR Investigators Dr. Address correspondence to Bruce Verchere, Child and Family Research Institute, 950 West 28th Ave, Vancouver, British Columbia, V5Z 4H4, Canada. Bruce Verchere about beta cells and his lab's work to better understand them. Verchere’s research aims to understand the function of pancreatic islet beta cells and Liked by Bruce Verchere Latest Spaeth lab publication! Very proud of the lab's hard work!! https://lnkd. Bruce Verchere, professor in the departments of pathology & laboratory medicine and surgery, director of the Centre for Molecular Medicine and Therapeutics Oct 2, 2013 · Dr. He is also the chair of the National Research Council at the Canadian Diabetes Association, and chair of the Canadian Institutes of Health Research’s Diabetes Dr. We are pleased to announce Dr. , University of British Columbia External Panel/Investigators Meeting (In person only for EP, PIs, and NIH Staff) Pathology and Laboratory Medicine - University of British Columbia The initial step in successful islet transplantation is procurement of healthy donor islets. My research will be focusing on the role the immune system plays in the development and or protection from diabetes and the damage of islet cells that accompanies the disease. Sloop, C. Bruce Verchere, PhD Josep Vidal, MD, PhD Sakeneh Zraika, PhD Nov 14, 2023 · November 14 is #DiabetesAwarenessDay. Verchere. I will be carrying out a 6 months research internship in the Verchere’s Lab, which is part of the BC Children's Hospital Research Institute. Bruce Verchere, PhD Senior Associate Editor, Diabetes Professor, Depts. Bruce Verchere, who introduces the network and its goal of bringing diabetes researchers together to ultimately find a cure for diabetes. Yi-Chun Chen (BC) is a postdoctoral fellow working in Dr. ca 2143 In the present study, we assessed the capacity of CCL22 to protect transplanted islets in the context of alloimmunity. Bruce Verchere Head, Diabetes Research Program, CFRI Professor, Departments of Pathology & Laboratory Medicine and Surgery, UBC Irving K Barber Yesterday, Dr. Given the limited number of donor pancreata selected for islet isolation and that islets from multiple donors are typically required to obtain insulin independence, it is critical to improve pancreas procure … Feb 23, 2021 · This study reveals that T cells are a part of the normal islet immune population in mouse and human islets, and accumulate in islets during ageing in a body weight-independent manner. Blue Trust is a complex tale of high drama brilliantly told by one of Canada's most admired investigative journalists. in/gZM3xabG Liked by Bruce Verchere I am based out of Dr. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities. Bruce Verchere as the Director of the Centre for Molecular Medicine and Therapeutics (CMMT) - cmmt. Series launches: Tuesday, February 16 at 1 pm (PST) Dr Bruce Verchere Director Centre for Molecular Medicine and Therapeutics UBC Professor, Faculty of Medicine, Departments of Pathology & Laboratory Medicine and Surgery Irving K Barber Chair in Diabetes Research Location: BC Children’s Hospital Research Institute Supervisor: Bruce Verchere Short bio: I am a PhD student working under the supervision of Dr. Bruce Verchere’s lab at BC Children’s Hospital Research Institute and the Department of Pathology and Laboratory Medicine at the University of British Columbia. Location: BC Children’s Hospital Research Institute (BCCHR) Supervisor: Bruce Verchere Jun 21, 2024 · Discover Company Info on VALENTINUS RESOURCES, INC. Biomarkers are used to Blue Trust is the story of Bruce and Lynne Verchere, and the author Arthur Hailey. Phoebe Lu, Director of Research Services at BC Children's Hospital Research Institute (BCCHR) accepted the University of British Columbia Science Co-op Employer Recognition Award on behalf of BCCHR. Who is this man? And why does he figure in the Mulroney-Schreiber story? The short answer is that Verchere was the tax Jan 1, 1998 · Blue Trust has all the ingredients of a gripping thriller -- except it's all true. %A Ivison,Sabine %A Verchere,C. Impairments in propeptide processing and secretory function, along with the loss of these vital cells, is demonstrable not only in those in whom the diagnosis is established but typically also in individuals who are at increased risk of developing the disease. The functional maturation and dedifferentiation of adult β-cells is central to diabetes pathogenesis and to β-cell replacement therapy for the treatment of diabetes. #Lifetimeachievement Apr 3, 2024 · Dr. %A Crome,Sarah Q. Verchere's research is aimed at understanding how insulin-producing beta cells normally function and why they are dysfunctional and/or are destroyed in both type 1 and type 2 diabetes. Bruce Verchere Departments of Surgery and Pathology & Laboratory Medicine BC Children’s Hospital Research Institute Centre for Molecular Medicine and Therapeutics Apr 8, 2014 · Department of Pathology and Laboratory Medicine Faculty of Medicine Rm. Carriers of CPE mutations have elevated plasma proinsulin and develop severe obesity and hyperglycemia. Bruce Verchere) Jennifer Grants, Doctoral Student (PI: Dr. 36 - Biomarkers of Islet Function Presenter: Bruce, Verchere, Vancouver, Canada Authors: Jun 1, 2017 · 1 Departments of Surgery and Pathology & Laboratory Medicine, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada. Bruce Verchere 4 Daniël H. Orban & C. Instagram, Twitter, Facebook, TikTok profiles, and images on IDCrawl - free people search. Biosketch: C. From beta cells to bedsides: A 2018 update on diabetes research in British Columbia Laboratory and clinical investigators in BC are making notable discoveries as they collaborate to reach a better understanding of diabetes, especially regarding pancreatic beta cell biology, obesity, and autoimmunity. Jan 15, 2020 · ABOUT THIS EPISODE In our first episode, host Krista Lamb talks to BC Diabetes Research Network lead and UBC professor Dr. ca Office: (604) 875-2490 (604) 875-3883 Dec 1, 2022 · Dr. Jun 16, 2017 · Hailey didn't approve of the relationship as he feared Verchere was after his fortune too, but his daughter was in love and eventually became pregnant with twins. Verchere’s work has led to the discovery of new beta cell biomarkers and promising approaches to slow immune attack in T1D and islet transplants. Calvin Kuo Bruce Verchere, BCCHR Diabetes Frédéric Picard, University Laval Dana Miller, University of Washington, USA Javier Irazoqui, University of Massachusetts Medical School, USA Amy Walker, University of Massachusetts Medical School, USA Seung-Jae Lee, Pohang University of Science and Technology, Korea Jenny Watts, Washington State University, USA Experience: Centre for Molecular Medicine and Therapeutics · Location: Vancouver · 500+ connections on LinkedIn. Beta cells play a big role in diabetes, and what we know about them continues to evolve. In the late 1980s Bruce and Lynne Verchere had it all. Dec 8, 2021 · “The JDRF Centre of Excellence at UBC will transform Type 1 diabetes research in Canada, sparking new collaborations, removing barriers and accelerating progress toward a cure,” says Dr. Verchere Lab In diabetes mellitus the pancreas’ insulin-producing beta cells have impaired function or are destroyed, resulting in deficient insulin secretion. Barber Chair in Diabetes Research Aug 4, 2025 · 14 6. Shubhayan Sanatani Dr. Jul 21, 2020 · Laval, Québec, Québec, Canada. Joel Montane, 1 Loraine Bischoff, 1 Galina Soukhatcheva, 1 Derek L. Hear from Dr. Barber Chair in Diabetes Research, University of British Columbia Diabetes is a multifactorial metabolic disorder defined by the loss of functional pancreatic insulin-producing β-cells. Bruce Verchere’s lab. Experience: Centre for Molecular Medicine and Therapeutics · Location: Vancouver · 500+ connections on LinkedIn. School of Biomedical Engineering, University of British Columbia 18 17 Correspondence to: Megan Levings, mlevings@bcchr. 22, 2018 Location: LSC3 Hosted by Drs. Bruce Verchere, Director of the Centre for Molecular Medicine and Therapeutics and Dr. Carl De Boer Feb 26, 2008 · Unless you were watching Mr. She earned her PhD in cellular and integrative physiology from Indiana University School of Medicine in the United States. The Diabetes Research Program includes six laboratories whose research covers aspects of the immunopathology, cell biology, biochemistry, virology, and genetics of type 1 diabetes. , Vancouver, British Columbia, Canada, V5Z 4H4. Bruce Verchere’s lab at BC Children’s Hospital, and is a panellist at the upcoming Women in Science event on February 9. While at the Verchere lab I have gained expertise in pancreatic islet biology, and my research was focused on understanding the role of human islet amyloid polypeptide precursors in islet amyloid toxicity and beta cell dysfunction. We would like to show you a description here but the site won’t allow us. Most of the volunteer musicians in this chamber music ensemble work at CFRI: George Chung, Postdoctoral Fellow (PI: Dr. Bruce Verchere, professor at the BRIMM - University of British Columbia, as the recipient of the 2023 Lifetime Achievement Award. Peter Zandstra, Investigator and Director at the UBC School of Biomedical Engineering, who were recently awarded funding from Canada's Stem Cell Network for their project entitled, "Leveraging stem cells to create an Apr 10, 2025 · Interlaboratory Transfer of a Novel Assay for Glucagon and Oxyntomodulin Jessica Becker, M. Garth Warnock C. Rideout and Kopp The Verchere laboratory enjoys a recent freezer cleaning. Becker, Austin Taylor, Guo-Fang Zhang, Kyle W. %D 2023 %J Frontiers in Immunology %C %F %G English %K CITESeq,Tissue immunity,Flow Cytometry,Pancreas,Single cell RNA seq %Q %R 10. Francis Lynn, as well as Dr. Netter MD School of Medicine Jessie Yasko, Ph. Amyloid forms within pancreatic islets in type 2 diabetes from aggregates of the β-cell peptide islet amyloid polypeptide (IAPP). Profile Bruce Verchere bruceverchere. *Co-senior authors. Shazhan Amed Dr. Bruce was a respected lawyer in Montreal; Lynne, a computer software entrepreneur. Gregor Reid Dr. We sought to determine the contribution of resident islet macrophages to IAPP-induced inflammation … Oct 24, 2013 · BC Children's Hospital Research Institute - Home-grown ensemble Laboratory Culture wowed us with their classical oeuvre. Bruce Verchere is a Professor in the Departments of Surgery and Pathology & Laboratory Medicine at the University of British Columbia (UBC). We aimed to determine whether loss of Cpe in pancreatic β-cells disrupts proinsulin processing and accelerates development of diabetes and Bruce Verchere posted a video on LinkedInJoin Sarah Lubik and Azadeh Goudarzi PhD, MBA for an upcoming webinar in collaboration with NanoMedicines Innovation Network (NMIN) on Business of Science I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Mar 26, 2025 · C. The candidate will gain diverse expertise across a variety of experimental systems including stem cell differentiation, genetic engineering I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Kevin J. Feb 26, 2008 · Unless you were watching Mr. Despite its im … I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Autoimmune (type 1) diabetes mellitus results from the destruction of insulin-producing pancreatic beta cells by T lymphocytes. %A Budd,Matthew A. Orban, 1 Timothy J. Bruce Verchere Chair, UBC Professor, Faculty of Medicine, Departments of Surgery & Pathology & Laboratory Medicine, BC Children’s Hospital Research Institute bverchere@bcchr. This time it’s into the lives of Montreal tax lawyer Bruce Verchere and his wife Lynne – and a myriad of other characters drawn, over the years, into their world. Join Facebook to connect with Bruce Verchere and others you may know. PH Congratulations to BCCHR Investigators Dr. , University of Washington Islet Prohormone Processing: proIAPP Forms as Novel Beta Cell Biomarkers in Diabetes Bruce Verchere, Ph. He also describes his lab’s ongoing research on beta cell function and biomarkers to better understand and predict diabetes. Aug 19, 2022 · Hyperglycemia and type 2 diabetes (T2D) are caused by failure of pancreatic beta cells. He is a prominent member of both the UBC and BC Children's Hospital Research Institute (BCCHR) communities. Location: BC Children’s Hospital Research Institute Supervisor: Bruce Verchere Sep 28, 2021 · The pathogenesis of hyperglycemia observed in most forms of diabetes is intimately tied to the islet β cell. Bruce Verchere, and Dr. Bruce Verchere focuses on better Jun 28, 2021 · The pathogenesis of hyperglycemia observed in most forms of diabetes is intimately tied to the islet β cell. The ratio of proIAPP1-48-to-IAPP immunoreactivity may have value as a biomarker of β-cell stress and dysfunction. Hoofnagle This study was a massive team effort driven by Neurimmune and involving numerous academic labs in Europe and the Verchere lab at BC Children's Hospital Research Institute. Bruce Verchere (Pathology and Laboratory Medicine/Surgery), Dr. Series launches: Tuesday, February 16 at 1 pm (PST) Dr Bruce Verchere Director Centre for Molecular Medicine and Therapeutics UBC Professor, Faculty of Medicine, Departments of Pathology & Laboratory Medicine and Surgery Irving K Barber Chair in Diabetes Research 2019 ARCHIVE Show All Records Show All Records News IT News Awards Departmental Exams Events 2019 2019 2018 2017 2016 2015 2014 2013 TIP! Click on table header to sort on the corresponding column. ca Bruce is the UBC Departments of Surgery and Pathology & Laboratory Medicine, head of the Canucks for Kids Fund Childhood Diabetes Laboratories at BC Children's Bruce Verchere Professor of Medicine University of British Columbia and BC Children's Hospital Research Institute Verified email at mail. Despite advancements in islet procurement and immune suppression that have increased islet transplant survival, graft function progressively declines, and many recipients return to insulin dependence within a few years posttransplant. A growing body of evidence suggests that beta-cell failure in type 2 diabetes correlates with the formation of pancreatic islet amyloid deposits, indicating that … Dr. Bruce Verchere's Lab, BC Children's Hospital; Master of Science Student, Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia (UBC) Lindsay Pallo and Raelyn Gallant know too well how wonderful it would be to cure, prevent, or at least improve treatment for diabetes. Bruce Verchere "A better understanding of how beta cells are produced during development has led to improvements in the production of insulin-producing cells from stem cells that are now being used in clinical transplantation trials in type 1 diabetes," said Dr. Bruce Verchere, PhD, Departments of Surgery and Pathology & Laboratory Medicine, BC Children’s Hospital, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada. Dominka shares her interesting story of how she came to finish her PhD in Dr Bruce Verchere’s Laboratory in the Canucks for Kids Fund Childhood Diabetes Laboratories located at the BC Children’s Hospital Research Institute. Bruce Verchere Canadian Institutes of Health Research Fall 2024 Project Grant Priority Announcements Read More Dr. The Research Both the Chantler and Verchere laboratories are part of the Diabetes Research Program at the Child and Family Research Institute in Vancouver, British Columbia. Rusung Tan) Jaques Courtade, Doctoral Student (PI: Dr. Bruce Verchere 1,2 1 Departments of Pathology and Laboratory Medicine, Child and Family Research Institute, 2 Department of Surgery, and 3 Department of Cellular and Physiological Sciences, University of British Columbia One hundred years have passed since the discovery of insulin-an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. , we are always thrilled to see past work from our amazing team of scientists get published! At the Bruce Verchere lab, Heather Denroche, provided expertise in I am excited to be working alongside Dr. Prediction of cell-mediated autoimmune diseases by direct detection of autoreactive T cells in peripheral blood has proved elusive, in part because of their low frequency a … Cellular Mechanisms of CCL22-Mediated Attenuation of Autoimmune Diabetes Article Mar 2015 Loraine Helena Bischoff Sigrid Alvarez Derek L Dai [] C Bruce Verchere I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune C. From L to R: Agnieszka Klimek; Bruce Verchere; Annette Plesner; Genny Trigo; Galina Soukhatcheva; Lucy Marzban; and Kate Potter “We are excited about our impending move in January 2008 into a new addition to the CFRI, including ~22,000 sq ft of research space”. Utzschneider, MD C. James Lim Dr. The β-cell is subject to a number of other stressors … Jun 16, 2025 · The team Dr. Potter, View ORCID ProfileLindsay P. Abstract β-Cell replacement by islet transplantation is a potential curative therapy for type 1 diabetes. Bruce Verchere, Andrew N. Vallance 3 C. Bruce Verchere, BC Children’s Hospital Research Institute, Professor, Faculty of Medicine UBC and Director, Centre for Molecular Medicine and Therapeutics and Irving K Barber Chair in Diabetes Research: I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Feb 4, 2025 · Francis Lynn, General Surgery/School of Biomedical Engineering Co-PIs: Megan Levings (Surgery/School of Biomedical Engineering); Bruce Verchere (Pathology & Laboratory Medicine/Surgery) Building better beta cells in order to improve stem cell-derived islet transplantation outcomes *Conditional award at time of posting Brian MacVicar, Psychiatry Mar 29, 2023 · On this episode, host Krista Lamb speaks with Dr. Stefan Taubert) Paul Orban, Research C Bruce Verchere 12 BC Children’s Hospital Research Institute and Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V5Z 4H4, Canada 13 Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada 14 Department of Surgery, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada Find articles by C Bruce Verchere 12,13,14 She works as a graduate research assistant in Dr. 1107582 %W %L %M %P %7 %8 2023-March-01 %9 Methods %+ C. Researchers affiliated with the Division of Endocrinology research include: Dr. It wasn’t until she had worked in an entomology lab as an undergrad that she found her interests lay a little outside the mainstream. Francis Lynn (Cellular & Physiological Sciences/School of Biomedical Engineering/Surgery), Dr. Bruce Verchere’s laboratory at the University of British Columbia. Mar 24, 2017 · Address all correspondence and requests for reprints to: C. D Professor Depts of Surgery and Pathology & Laboratory Medicine University of British Columbia 12:30 PM Thursday, Nov. Megan Levings, who were awarded $600,000 from Canada's Stem Cell Network… Director of Formulation Development at Integrated Nanotherapeutics · Experience: Integrated Nanotherapeutics Inc. Kieffer, 2,3 Rusung Tan, 1 and C. By … Nov 24, 2022 · “The annual meeting was an inspiring day where Centre researchers shared progress from our first year of operation, and patient partners shared their stories of living with T1D,” said Bruce Verchere, one of the project leads at the Centre. Virtual Global Transplant Lab (vGTL) on Biomarker Validation and Implementation 2. The desperate affair and dangerous ultimatum that followed provide this true story with a chilling climax. Megan Levings, Dr. Scheithauer 1,2 * Elena Rampanelli 2 Max Nieuwdorp 1,2 Bruce A. At this time Verchere's wife clued into the money situation and threatened serious legal consequences unless Bruce left his mistress and returned to her. The Blue Trust was a tax shelter, set up for Bruce and Lynne’s two sons David and Michael, a safeguard for wealth well into their futures. Bruce Verchere Islet amyloid polypeptide (IAPP) aggregates to form amyloid fibrils in patients with type 2 diabetes and acts as a potent stimulus for interleukin (IL)-1β secretion by bone marrow-derived macrophages. These aggregates are toxic to β-cells, inducing β-cell death and dysfunction, as well as inciting islet inflammation. Bruce Verchere, BCCHRI and UBC Expertise: beta cell physiology and beta cell regeneration Dr. Verchere is the director of the BC Diabetes Research Network and a Scientist at the BC Children's Hospital Research Institute in Vancouver. Peter Zandstra (Medical Genetics/School of Biomedical Engineering) Leveraging stem cells to create an engineered model of type 1 diabetes Jan 12, 2023 · C. Sep 12, 2023 · Read about some of the exciting discoveries and progress our researchers have made in the last year! Faculty spotlights from the Dept of Pediatrics include: Dr. Francis Lynn & Dr. I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune and involving numerous academic labs in Europe and the Verchere lab at BC Children's Hospital Research Institute. This leads to high blood glucose levels and later complications, including kidney disease and blindness. Bruce Verchere Congratulations to Dr. Islet antigen-specific Tregs have more potent therapeutic effects than polyclonal cells, but their low frequency is a barrier for clinical application. The T cell differentiation work will include collaborations with Zandstra. · Education: The University of British Columbia · Location: Vancouver · 219 connections on LinkedIn. On this week's podcast episode, Diabetes Canada funded researcher, Dr. Jul 23, 2024 · Francis Lynn (Surgery/School of Biomedical Engineering) UBC Medicine Co-PI (s): Bruce Verchere (Surgery/Pathology and Laboratory Medicine) Building better beta cells in order to improve stem cell-derived islet transplantation outcomes Priority Announcement Area: Nutrition, Metabolism and Diabetes Christopher Maxwell (Pediatrics) Looking for Bruce Verchere? Found 3 people named Bruce Verchere. - Biolegend Mason Yeh, Postdoc - UCB Biosciences Prem Shrestha, Postdoc - Postdoc, Yi Wu, UConn Health Raj Luxmi, Postdoc UConn Health - Postdoc, Steve King, UConn Health Get the details of Bruce Verchere's verified business profile including email address, phone number, work history and more. Now they’re conducting diabetes research in Dr. Tel: +1-604-875-2490; Fax: +1-604-875-2373; E-mail: bverchere@cfri. Rusung Tan, Department of Pathology & Laboratory Medicine, BCRICWH, 950 W 28th Ave. Keegan Korthauer: The Korthauer Laboratory Cracking The Code Dr. van Raalte 1,2 Hilde Herrema 2 Dec 20, 2016 · Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada Jaques A. Obese individuals with or without T2D were included from two independent My lab is looking for a research technician to help us with our next generation sequencing, bioinformatics, and genetic engineering projects! If you are or know someone who is interested, apply Cell therapy with human Interleukin 10–producing ILC2s enhances islet function and inhibits allograft rejection Sarah J. Lindsay Pallo and Raelyn Gallant were both diagnosed with type 1 diabetes as children. To celebrate, we're highlighting the outstanding work of Vriti Bhagat, a PhD student in Dr. ca or roo@interchange. Bruce Verchere a Department of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada;b BC Children’s Hospital Research Institute, Vancouver, BC, Canada;c Centre for Molecular Medicine and Therapeutics, The University of British Columbia, Vancouver, BC, Canada;d Department of Surgery, The University of The Verchere laboratory enjoys a recent freezer cleaning. Jul 1, 2011 · Joel Montane, 1 Loraine Bischoff, 1 Galina Soukhatcheva, 1 Derek L. Bruce Verchere and his lab. Nov 23, 2022 · Dr. 875. 20 Year Service Awards Dr. Nov 14, 2023 · To celebrate, we're highlighting the outstanding work of Vriti Bhagat, a PhD student in Dr. in Baton Rouge, LA, such as Contacts, Addresses, Reviews, and Registered Agent. Since the development of the Edmonton Islet Transplantation Protocol, islet transplantation has given new hope to patients with type 1 diabetes. Bruce Verchere is a professor in the departments of surgery and pathology & laboratory medicine at the University of British Columbia (UBC), and head of the Diabetes Research Program at the Child & Family Research Institute. 20 hours ago · Read American Comic: As Bruce Wayne, Inheriting Arkham Knight at the Start / 美漫：开局继承阿卡姆骑士 raw light novel translation in English - WTR-LAB Sep 19, 2018 · Islet prohormone processing studies in the Verchere laboratory are supported by funding from the Canadian Institutes of Health Research (CIHR; PJT—153156) and (JDRF 3‐SRA‐2014‐39‐Q‐R). Bruce Verchere Canadian Institutes of Health Research Priority Announcement Grant Read More Dr. Bruce Verchere Location: BC Children’s Hospital Research Institute Supervisor: Bruce Verchere Sep 19, 2018 · Biosynthesis of peptide hormones by pancreatic islet endocrine cells is a tightly orchestrated process that is critical for metabolic homeostasis. He was a successful tax lawyer whose clients included Brian Mulroney, and bestselling novelist Arthur Hailey. Bruce Verchere or Dr. She works as a graduate research assistant in Dr. Bruce Verchere Bruce Verchere is on Facebook. … Jan 29, 2016 · Bruce Verchere, PhD, Professor, Departments of Surgery and Pathology & Laboratory Medicine; Head, Diabetes Research Program, Child & Family Research Institute (CFRI), BC Children’s Hospital and the Irving K. Sep 21, 2025 · Canqi Cui, Danielle C. Hull, PhD Jenny Tong, MD, MPH Kristina M. Bruce Verchere's Lab at BC Children’s Hospital Research Institute where I study the regenerative properties of tissue-resident myeloid cells from healthy and diseased human donor tissue. Wang, Paul Yen, Derek L. Grimsrud, Jessica O. My research area uses genetically-engineered human embryonic stem cell derived insulin producing cells Lab and cores: This project harnesses expertise across the centre, with opportunities to work with Levings, Verchere and Lynn to learn stem cell-based differentiation protocols. Bruce Verchere, professor in the departments of pathology & laboratory medicine and surgery, director of the Centre for Molecular Medicine and Therapeutics Current PhD student in the University of British Columbia's Pathology and Laboratory Medicine Program based out of Dr. Dr. Dai, Galina Soukhatcheva, Paul C. I enjoy all things data -- from generation to analysis and visualization -- and am a single cell RNA sequencing "wet-bioinformatician. %A Monajemi,Mahdis %A Reid,Kyle T. Impairments in propeptide processing and secretory function, along with the loss of these vital cells, is demonstrable not only in those in whom the diagnosis is established but typically als … In this episode, Monica Westley, PhD, catches up with Bruce Verchere, PhD, the winner of the 2023 Lifetime Achievement Award in Diabetes. %A Colpitts,Sarah J. View Bruce Verchere’s profile on LinkedIn, a professional community of 1 billion members. Sep 19, 2025 · Duke diabetes and obesity researchers show alpha cells in the pancreas unexpectedly churn out potent, insulin-boosting GLP-1 to help control blood sugar. Peter Zandstra, Investigator and Director at the UBC School of Biomedical I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Share your videos with friends, family, and the world Virtual Global Transplant Lab (vGTL) on Biomarker Validation and Implementation 2. Though comprising only a small subset of the immune cells within islets, islet T cells may play a role in the physio … Affiliation 1 Department of Pathology and Laboratory Medicine, University of British Columbia and Child and Family Research Institute, Vancouver, BC, Canada. Nov 13, 2023 · Courtney Ostromecki - Verchere Lab Genome engineering of regulatory T cells to improve cell therapy for islet transplantation and type 1 diabetes Sonya Mangat - Levings Lab I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune . Bruce Verchere 1,2 1 Departments of Pathology and Laboratory Medicine, Child and Family Research Institute, 2 Department of Surgery, and 3 Department of Cellular and Physiological Sciences, University of British Columbia Researchers affiliated with the Division of Endocrinology research include: Dr. View Sam Chen’s profile on LinkedIn, a professional community of 1 billion members. Woodward Professor Department of Surgery, UBC Co-Director, Ike Barber Human Islet Transplant Laboratory and British Columbia Islet Transplant Program Dr. I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune It is with great pleasure that we announce the appointment of Dr. Zemaitis Staff Scientist at Pacific Northwest National Laboratory Dusan Velickovic Pacific Northwest National Laboratory Lye Meng Markillie EMSL (PNNL) Bruce Verchere Professor of Medicine University of British Columbia and BC Children's Hospital Research Institute Sarah Franklin University of Utah Check out “Heard on the Street” recorded during Day 2 of Islet Study Group 2023. This is based on laboratory-based studies involving human islets as well as clinical studies employing intensive insulin therapy, thiazolidinediones, bariatric surgery, short-acting glucagon-like peptide (GLP)-1 receptor agonists and a promising new class of diabetes drugs, sodium-glucose-linked transporter (SGLT)-2 inhibitors. Beta cells first produce large proteins that are then “cut” down into insulin. Bruce Verchere Head, Diabetes Research Program, CFRI Professor, Departments of Pathology & Laboratory Medicine and Surgery, UBC Irving K Barber Department of Cellular and Physiological Sciences Bruce Verchere, Ph. Bruce Verchere, Director presenting 20-year service awards to Dora Pak, Wasserman Lab Research Manager, Yanbo Yan, Technician, Transgenic Facility, and William Yue, Stores Manager. From L to R: Agnieszka Klimek; Bruce Verchere; Annette Plesner;<br /> Altered prohormone processing, such as with proinsulin and pro-islet amyloid polypeptide (proIAPP), has been reported as an important feature of prediabetes and diabetes. Bruce Verchere, BSc MSc PhD Professor Departments of Surgery and Pathology & Laboratory Medicine Head, Diabetes Research Program City: Vancouver Hospital Authority: Vancouver Coastal Health Address: BC Children’s Hospital Research Institute Room A4-181 950 West 28 th Avenue Vancouver, BC V5Z 4H4 Phone: 604. 36 - Biomarkers of Islet Function Presenter: Bruce, Verchere, Vancouver, Canada Authors: Series launches: Tuesday, February 16 at 1 pm (PST) Dr Bruce Verchere Director Centre for Molecular Medicine and Therapeutics UBC Professor, Faculty of Medicine, Departments of Pathology & Laboratory Medicine and Surgery Irving K Barber Chair in Diabetes Research Head, Diabetes Research Program, BCCHR Dr Shazhan Amed, MD, FRCPC, MSc. Co-Founder & Director, Preclinical DevelopmentJosh Zaifman, PhD This study was a massive team effort driven by Neurimmune and involving numerous academic labs in Europe and the Verchere lab at BC Children's Hospital Research Institute. Korthauer began her career with a general interest in biology, ecology, and medicine. M. James Shapiro and the team at the University of Alberta in Edmonton, Canada. The role of the gut microbiota in T2D has been studied, but causal links remain enigmatic. Islet amyloid is a pathologic characteristic of the pancreas in type 2 diabetes comprised mainly of the beta-cell peptide islet amyloid polypeptide (IAPP; amylin). Bruce Verchere's lab. Nov 29, 2022 · Ranked among the world’s top medical schools with the fifth-largest MD enrollment in North America, the UBC Faculty of Medicine is a leader in both the science and the practice of medicine. IAPP has been reported to act as a Jul 23, 2019 · It is with great pleasure that we announce the appointment of Dr. of Surgery and Pathology & Laboratory Medicine University of British Columbia Irving K. – Listen to Heard on the Street: Bruce Verchere, PhD, University of British Columbia by TheSugarScience Podcast- curating the scientific conversation in type 1 diabetes instantly on your tablet, phone or browser - no downloads needed. E-mail: verchere@interchange. My interest in cell therapies for diabetes stems from my previous research experience at the University of Florida where I completed my master’s program in Biomedical Engineering. Bruce Verchere's 229 research works with 8,781 citations and 7,314 reads, including: Top-Down Proteomics of Mouse Islets With Beta Cell CPE Deletion Reveals Molecular Details in Prohormone Dec 1, 2022 · Biography: Bruce Verchere PhD is a Professor in the Departments of Surgery and Pathology & Laboratory Medicine at the University of British Columbia, investigator at the Childhood Diabetes Laboratories at BC Children’s Hospital Research Institute, and Director of the UBC Centre for Molecular Medicine and Therapeutics. Read about their lived experience and how that enriches their work. Date Title Category Image The Research Both the Chantler and Verchere laboratories are part of the Diabetes Research Program at the Child and Family Research Institute in Vancouver, British Columbia. Mehul Sharma Dr. 3389/fimmu. Rebecca L. We have interests in understanding the mechanisms that lead to beta cell failure in type 2 diabetes, including the role of islet amyloid and islet inflammation. Apr 1, 2025 · Dr. We used a pulse-chase approach to investigate the kinetics of processing and secretion of the IAPP precursor, proIAPP, in beta cells. His research aims to understand how insulin Biography Dr. Bruce Verchere's Lab at BC Children's Hospital Research Institute in May 25, 2016 · The grant will enable the labs, led by Bruce Verchere, to obtain state-of-the-art technology. ubc. The mission of the Diabetes Research Institute Foundation Canada (DRIFCan) is to directly fund cure-based diabetes research conducted by Dr. Gray, Kimberley El, Alex Chen, Paul A. social did:plc:shpmqcwj6sidmjf74ulrzfpk Type 2 diabetes is associated with progressive beta-cell failure manifest as a decline in insulin secretion and increasing hyperglycemia. To generate Tregs that recognize islet antigen … Jan 1, 1998 · Then Bruce Verchere fell in love. She is now a UBC doctoral student studying the chronic condition, alongside Raelyn Gallant who also lives with T1D and is a master of science student, in Dr. Bruce Carleton Dr. Schreiber's appearance before the Commons' Ethics Committee on February 25, you would never know that he raised, again and again, the name of Bruce Verchere. To identify additional epitopes, HLA c … It is with great pleasure that we announce the appointment of Dr. 2023. Barber Chair in Diabetes Research Jul 1, 2017 · The β cells in T1D and islet transplants have impaired processing of the proIAPP1-48 intermediate. Leander, Sarah M. Sep 1, 2023 · Carboxypeptidase E (CPE) facilitates the conversion of prohormones into mature hormones and is highly expressed in multiple neuroendocrine tissues. Dai, 1 Gijs Hardenberg, 2 Megan K. bsky. Series launches: Tuesday, February 16 at 1 pm (PST) Dr Bruce Verchere Director Centre for Molecular Medicine and Therapeutics UBC Professor, Faculty of Medicine, Departments of Pathology & Laboratory Medicine and Surgery Irving K Barber Chair in Diabetes Research Beta‐cell Prohormone Convertase 1/3 Plays a Larger Role in Glucose Homeostasis Than Beta‐cell Prohormone Convertase 2 in Mice Article Apr 2020 Austin James Yi-Chun Chen C. With Bruce Verchere, PhD, is a Professor in the Departments of Pathology & Laboratory Medicine and Surgery at the University of British Columbia (UBC), head of the Diabetes Research Program at the Child & Family Research Institute (CFRI) at BC Children’s Hospital, and the Irving K Barber Chair in Diabetes Research. Francis Lynn and Dr. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care professionals, making remarkable discoveries, and helping to create the pathways to Relevant Thesis-Based Degree Programs Pathology and Laboratory Medicine, Master of Science Pathology and Laboratory Medicine, Doctor of Philosophy Surgery, Master of Science Women+ and Children's Health Sciences, Master of Science Women+ and Children's Health Sciences, Doctor of Philosophy Our laboratory is focused on understanding how islet beta cells normally function and how they become dysfunctional in diabetes, and following transplantation. The book opens with a death. The decades since that momentous achievement have brought ever more rapid innovation and advancement in diabetes research and clinical care. Like solid organ transplantation, one of the biggest challenges islet transplantation faces is the shortage of available donor tissue. Apr 8, 2014 · Department of Pathology and Laboratory Medicine Faculty of Medicine Rm. PH 4 Department of Surgery and Department of Pathology and Laboratory Medicine, BC Children's Hospital Research Institute and University of British Columbia, Vancouver, British Columbia, Canada. For people with type 1 diabetes, this process doesn’t work well, and as a result their blood is full of these larger proteins. Bruce Verchere, PhD Bruce Verchere is a Professor in the Departments of Surgery and Pathology & Laboratory Medicine at the University of British Columbia (UBC), head of the Diabetes Research Program at the Child & Family Research Institute at BC Children’s Hospital, and the inaugural Irving K Barber Chair in Diabetes Research at UBC. ORCID record for Bruce Verchere. Colpitts 1,2 1,2 , Sinthuja Jegatheeswaran Oct 18, 2021 · Elevated islet prohormone ratios as indicators of insulin dependency in islet transplant recipients View ORCID ProfileYi-Chun Chen, Agnieszka M. Bruce Verchere, Investigator, Childhood Diabetes Laboratories and Director, Centre for Molecular Medicine and Therapeutics, BC Children's Hospital; Professor, departments of Surgery and Pathology & Laboratory Medicine, University of British Columbia C. Finding an alternati … Mar 14, 2017 · This is based on laboratory-based studies involving human islets as well as clinical studies employing intensive insulin therapy, thiazolidinediones, bariatric surgery, short-acting glucagon-like peptide (GLP)-1 receptor agonists and a promising new class of diabetes drugs, sodium-glucose-linked transporter (SGLT)-2 inhibitors. Like neuroendocrine peptides, insulin and other isle 4 Departments of Surgery and Pathology and Laboratory Medicine Pathology and Laboratory Medicine, BC Children's Hospital Research Institute, Centre for Molecular Medicine & Therapeutics, Vancouver, British Columbia, Canada. In our first episode, host Krista Lamb talks to BC Diabetes Research Network lead and UBC professor Dr. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide hormone that declines with diabetes progression. N. This ground breaking study showed that Neurimmune's anti-IAPP-oligomer (α-IAPP-O I look forward to working with you in 2020! Bruce Verchere, PhD Director, Centre for Molecular Medicine & Therapeutics BC Children’s Hospital Research Institute, Professor, Departments of Surgery and Pathology & Laboratory Medicine Irving K. I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Dominika is an incredible scientist, mother and positive influence in the lab. Klimek-Abercrombie, Kathryn J. Bruce Verchere Dr. D. I'm thrilled to see work from my postdoc in the Bruce Verchere lab in collaboration with Neurimmune AG published in Nature Communications! This study was a massive team effort driven by Neurimmune Jul 22, 2019 · Dear Colleagues, It is with great pleasure that we announce the appointment of Dr. Bruce Verchere, Dr. Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Bruce %A Levings,Megan K. Bruce Verchere posted images on LinkedInWe are so proud to celebrate the launch of LearnDiabetes, an interactive, multimedia platform that provides easy-to-understand education and training for Jul 22, 2019 · Dr. Bruce Verchere and his lab are studying how beta cells work, in order to protect them and their ability to produce insulin. Jun 18, 2025 · Co-Investigators: Dr. This is a testament to Dr Denroche’s collaborative skills and deep knowledge in diabetes and complex preclinical models. Bruce Verchere on receiving a Queen Elizabeth II Diamond Jubilee Medal for contributions to diabetes research. C. Bruce Verchere Investigator, BC Children's Hospital Director, Centre for Molecular Medicine and Therapeutics Professor, Department of Pathology & Laboratory Medicine and Department of Surgery, UBC Dr. Verchere is a highly accomplished researcher and Professor in the Departments of Pathology and Laboratory Medicine and Surgery. G227 – 2211 Wesbrook Mall Vancouver, BC Canada V6T 2B5 Aug 1, 2024 · Dr. The Centre’s research leads are: Dr. Stuart Turvey […] Dr. Series launches: Tuesday, February 16 at 1 pm (PST) Dr Bruce Verchere Director Centre for Molecular Medicine and Therapeutics UBC Professor, Faculty of Medicine, Departments of Pathology & Laboratory Medicine and Surgery Irving K Barber Chair in Diabetes Research Head, Diabetes Research Program, BCCHR Dr Shazhan Amed, MD, FRCPC, MSc. And members of this committee asked me, on February 14, several questions about Verchere. Bruce Verchere Department of Surgery, University of British Columbia, Vancouver, BC, Canada C. Where did you grow up? Taylor LaRese, Lab Tech - Medical Student, UConn Health Andrew Yanik, Lab Tech - Medical Student, Frank H. Aug 1, 2024 · Dr. uxih 4i1z9y 5l5e 4brnrmba mlwv fpae 8h d8w hcmd8 qh1sqb